Abstract

SYNTHESIS, COMPOSITION, GEOMETRY AND ANTIBACTERIAL ASSAY OF MONONUCLEAR SCHIFF BASE METAL COMPLEX DERIVED FROM 1H-INDOLE-2, 3-DIONE AND ANILINE

Parameshwari, Akila Ekamparam and *Shanmugam

Abstract

Mononuclear Schiff base metal complex of Mn(II) and its ligand have been synthesized with Schiff base derived from 1H-Indole-2, 3-dione and aniline. The structure of the ligand and its complex were characterized through physico-chemical studies. The molar conductance value of metal complex in DMF indicates the nonelectrolytic in nature. In IR spectra, the comparison of shift in frequency of the complex with the ligand reveals the coordination of donor atoms to the metal atom. The d-d transition of the metal complex provides information about the geometry of the complex and the transitions are in good agreement for the proposed octahedral geometry. The Schiff base and its complex have been screened for their in vitro antibacterial (staphylococcus aureus, bacillus subtilis, Eschericia coli and Klebsilla pneumonia) activity by paper disc method, it result confirms the mononuclear complex is more potent than free ligand.

Keywords: Staphylococcus aureus, bacillus subtilis, Eschericia coli and Klebsilla pneumonia.