Abstract

NOVEL DRUG DELIVERY SYSTEM FOR HERBAL FORMULATION IN CANCER TREATMENT

Deepa Mishra, Gayatri Panda, Puneet Kumar and Sangeeta Singh*

Abstract

Plant products have been used since in ancient times for various purposes. Nowadays, plants are being used as natural remedies for the treatment of various health concerns like allergies, wounds, burns, gastrointestinal disorders and even for cancer- (which proves food is medicine). Herbal drugs are good to use but difficult to process, identify, extract and deliver, thereby it needs modifications in order to overcome these problems, leading to the development of Novel Drug Delivery System (NDDS). NDDS is also beneficial in comparison to conventional methods for cancer treatment. It has modified the herbal drugs to increase their therapeutic value, reduce toxicity, achieve sustained and controlled release, improve solubility, bioavailability and increase patient compliance. NDDS includes various novel carriers like liposomes, phytosomes, microspheres, microemulsions, transferosomes, ethosomes and solidlipid nanoparticles. The purpose of this review is to outline several NDDS for delivery of herbal drugs for cancer treatment.

Keywords: Liposomes, phytosomes, microspheres, microemulsions, transferosomes, ethosomes and solid-lipid nanoparticles.