Abstract

STUDIES OF IRON (II) – TAXIM-OF SYSTEM

B. Srinivasa Rao, T. R. Kishore* and V. Suryanarayana Rao

Abstract

A new simple, accurate spectrophotometric method has been developed for the Analytical determination of Taxim-of and Iron(II) in pharmaceutical formulation is carried and based on a colour reaction between Taxim-of and Iron(II) forms yellow coloured complex in a buffer pH – 5. This method can be conveniently used for the determination of Iron(II) and Taxim-of, in the ranges of Iron(II) 0.698 – 4.98 μg/25ml and Taxim-of in the range of 1 to 6 mg/ml. The method is successfully applied for the determination of Taxim-of and Iron(II) in pharmaceutical formulation. Effect of various parameters, pH, metal ion concentration, drug concentration of solutions is studied. The optimum condition are established for the determination of Iron(II) and the drug.

Keywords: Spectrophotometric method1, Taxim-of and Iron(II) system.