Abstract

SYNTHEIS OF SILVER NANOPARTICLES FROM GYMNEMA SYLVESTRE LEAF AND EVALUATION OF THEIR IN VITRO ANTIDIABETIC ACTIVITY

Vijayakumari A. and Saratha V*.

Abstract

The environmental friendly synthesis of nanoparticles process is a revolutionary step in the field of nanotechnology. In the is study, the biosynthesis of silver nanoparticaes was carried out using Gymnema sylvestre leaf extract as reducing an agent UV-visible spectroscopy was used for identification of silver nanoparticles synthesis. The synthesized silver nanoparticles elctrons were characterized UVvisible spectrophotometry, Scanning Electron Microscopy (SEM) and Fourier Transform Infra red spectrorscopy (FTIR). In vitro antidiabetic properties of the bio synthesis silver nanoparticles were found to have high inhibitory activity. The assay result suggest that the presence of bio active compounds, AgNPs exhibit the dose dependent increase in inhibitory on α Amylase enzyme α-gulucosidase and Tyrosinase enzymes. These results indicated that AgNPs from Gymnema sylvestre leaf could be used as a source of antidiabetic agents.

Keywords: Gymnema sylvestre, Antidiabetic Activity, UV-visible spectra, Silver nanoparticles.