Abstract

INGREDIENTS IDENTIFICATION, PHYSICO-CHEMICAL AND HPTLC ANALYSIS OF VAJRAK GHRITA– A POLYHERBAL FORMULATION

*Dr. Shital G. Bhagiya, PhD Scholar, Prof. Anup B. Thakar, HOD, Dr. Nilesh Bhatt, Panchkarma Physician, Dr. Harisha C. R., HOD and Dr. V. J. Shukla, HOD

Abstract

Background: Vajrak Ghrita (VG) is mentioned in Ayurvedic classics as a therapeutic formulation to treat Kushtha (Skin diseases). The Ghrita was prepared with respective pharmacognostically identified ingredients those are Vasa (Justicia adhatoda Linn.), Guduchi (Tinospora cordifolia Miers.), Nimba (Azadirachta indica A. Juss), Patola (Luffa acutangula Linn.), Kantakari (Solanum surrattense Burm.f.), Karanj (Pongamia pinnata Linn.), Triphala. The base was Go-ghrita. All the ingredients have Kushthaghna properties. Materials and Methods: Powders of all ingredients were evaluated for their pharmacognostic study and finished product which is VG was evaluated for pharmaceutical analysis. Results: Some typical microscopic characters were found of Vasa, Guduchi, Nimba, Patola, Kantakari, Karanj, Triphala. Results obtained in pharmaceutical parameters of VG, Acid value 3.4, Refractive Index 1.4710, Iodine value 28, Saponification Value 296.47, Specific Gravity 0.9254, Loss on drying 0.15, pH value 3.5 are within limit mentioned by Ayurvedic Pharmacopoeia of India. High performance thin layer chromatography profile of VG powder showed similarities in number of spots. Conclusion: From the study, data developed can be espoused for laying down the standards for VG.

Keywords: HPTLC, Pharmacognostical, Pharmaceutical analysis, Vajrak Ghrita.