Abstract

INVESTIGATION OF PHYTOCHEMICAL SCREENING AND ANALGESIC ACTIVITY OF DIFFERENT EXTRACTS OF CUSCUTA CHITTAGONGENSIS LEAVES

Abdullah-Al-Mamun, Sabiha Ferdowsy Koly*, Md. Mukter Hossain, Shirajum Munira, Sonia Zaman and Md. Shah Amran

Abstract

The purpose of this study was to investigate the presence of phytochemical and determine the analgesic activity of Cuscuta chittagongensis. In Phytochemical screening, leaves contain different types of compound such as glycosides, alkaloids, flavonoids, tannin etc. Acetic acid and formalin induced method were performed to investigate the analgesic effect of leaves extracted with different solvent system. Diclofenac Na was used as standard. Cuscuta chittagongensis extracts were given orally to the 4 groups of experimental mice. Among these fractions the most potent activity was found in ethyl acetate extract which showed highest % of inhibition (69.15) at 200 mg/kg where standard (Diclofenac-Na) showed 80.44. From this result, it is clear that all the extracts of cuscuta chittagongensis contain analgesic activity. The inhibition increased as the dose of extract was increased.

Keywords: Cuscuta chittagongensis, acetic acid induced and formalin induced methods, analgesic activity.