Abstract

EVALUATION OF POLYHERBAL FORMULATION FOR WOUND HEALING ACTIVITY USING EXCISION MODEL

Prabhat Khare*, Neelima Goswami, Smita Khare, R B Goswami, A K Pathak

Abstract

A wound may be defined as a break in the epithelial integrity of the skin or may also be defined as a loss or breaking of cellular and anatomic or functional continuity of living tissue. Wound healing studies are mainly aim to detect various means and factor influencing healing process, so they could be either used or avoid in clinical practice to favorably alter the healing process. The present study aims to investigate the possible effect of polyherbal formulation containing Ageratum conyzoides, Ficus religiosa, Curcuma longa and Tamarindus indica on wound healing process. The wound healing property appears to be due to the presence of active principles, which accelerates the healing process and confers breaking strength to the healed wound. Further, wound healing activity by polyherbal formulation may be attributed to the synergistic action of the active phyto-constituents like alkaloids, saponins and terpenoids present in it.

Keywords: Wound healing, Ageratum conyzoides, Ficus religiosa, Curcuma longa and Tamarindus indica.