Abstract

PHYTOCHEMICAL SCREENING AND ANTIMICROBIAL ACTIVITIES OF ETHANOL EXTRACT OF KIGELIA AFRICANA (LAM) BENTH

N. Mohana Vaidegi, N. Padmapriya* and T. V. Poonguzhali

Abstract

The aim of our investigation was to evaluate the phytochemical and antibacterial activities of Kigelia africana. Phytochemical screening was carried from dried fruit powder followed by extraction with ethanol. Antibacterial activity were tested against the three bacterial strains namely Bacillus subtilis, Staphylococcus aureus, Salmonella typhi and fungal strain were tested against two fungal strains namely Epidermophyton floccusum and Candida albicans using disc diffusion method. The maximum zone of inhibition was seen against S. aureus with 21.1 mm while only mild zone of inhibition was observed in B. subtilis with 18.8 mm and least zone of inhibition was seen in S. aureus with 5.5 mm. In fungal activity the maximum zone of inhibition was seen against C. albicans with 21.1 mm while only mild zone of inhibition were examined in E. floccusum with 15.5 mm and least zone of inhibition was seen in C. albicans with 8.8mm at a concentration of 25μg/ mL respectively. The overall antimicrobial activity assessed from the above results indicates the presence of active constituents in the dried fruit extract and it can be used in pharmaceutical industry.

Keywords: Antimicrobial activity, well diffusion method, Kigelia aficana.