Abstract

PLANT AS ANTICOGULANT/ANTITHROMBOTIC AGENT

*Shikha Jain, CBS Dangi, Manpreet Kaur, Hardev Singh, Jaya Peter &Sushmit Kosta

Abstract

Thrombotic diseases such as myocardial or cerebral infarction are serious consequences of the thrombus formed in blood vessels. These diseases are important cause of mortality in developed and third world countries. Antithrombotic agents are used to prevent thrombosis and thrombolytic agents are used to dissolve the already formed clots in the blood vessels however, these drugs have certain limitations which cause serious and sometimes fatal consequences. Herbal preparations have been used since ancient times for the treatment of several diseases. Several plants used for the treatment of thromboembolic diseases in different systems of traditional medicine have shown anticoagulant or antithrombotic activity and such plants claimed in the traditional system still remain to be scientifically investigated. The review explains few traditional antithrombotic drugs and their side effects and mentioned few plants showing antithrombotic and anticoagulant in-vitro and in-vivo.

Keywords: Anti-coagulant activity, Antithrombolytic Activity, Prothrombin, plant, Coagulation factors.