Abstract

THE EFFICACY OF SACCHAROMYCES CEREVISIAE AND CANDIDA KRUSEI IN REDUCTION OF AFLATOXIN B1 THAT PRODUCED BY ASPERGILLUS FLAVUS IN VITRO

*Al-Saad L. A.

Abstract

Aflatoxin B1 (AFB1) is a potent hepatotoxic and hepatocarcinogenic mycotoxin produced by some filamentous fungi like Aspergillus flavus and Aspergillus parasiticus. This toxin widely contaminates food and feedstuffs causing health problems to the human and animals when consuming the contaminated food. This study compared between two of well-known biocontrol yeasts Saccharomyces cerevisiae (S.c.) and Candida Krusei (C.k.) in vitro to evaluate their efficiency in control A.flavus growth and AFB1 reduction. The results revealed a significant ability of both yeasts to inhibit fungal growth area (3.9, 8.14 mm2) respectively comparing with the control (71.34 mm2). Both yeast species (Sc. and C.k.) were significantly reduced 250 ng of AFB1 to the non-detectable levels after 48h of incubation in broth culture.

Keywords: Aflatoxin B1 Aspergillus flavus and Aspergillus parasiticus.