Abstract

MODERN ADVANCEMENT IN SUSTAINED RELEASE DRUG DELIVERY SYSTEM

Sharad S. Joshi*, Akash A. Jain, Dr. Surajj Sarode and Dr. Shashikant Barhate

Abstract

The oral route is the most popular route used for administration of drugs, which is due in part to the ease of administration, and to the fact that gastrointestinal physiology offers more flexibility in dosage form design than most other routes. The terms sustained release, prolonged release, modified release, extended release or depot formulations are used to identify drug delivery systems that are designed to achieve or extend a therapeutic effect by continuously releasing medication over an extended period of time after administration of a single dose. There are several reasons for attractiveness of these dosage forms: provides increased bioavailability of drug product, reduction in the frequency of administration to prolong duration of effective blood levels, reduces the fluctuation of peak trough concentration and side effects and possibly improves the specific distribution of the drug.

Keywords: SRDDS, Drug selection Criteria, Factors affecting SRDDS, Classification.