Abstract

SYNTHESIS, REACTIVITY AND BIOLOGICAL APPLICATIONS OF HALOVINYL ALDEHYDES: A REVIEW

Shankarsing Sardarsing Rajput* and Javed Hanif Mansoory

Abstract

Aim of our review is to provide an overview of the synthesis and diverse synthetic applications of halovinyl aldehydes, ranging from their preparation, transformations and important chemical applications in organic synthesis. These are important synthetic tools in organic synthesis. A large number of research groups have been reported their significant contributions on synthesis and reactivity of halovinyl aldehydes. These become important precursors for construction and development of new types organic derivatives with biological activity.

Keywords: Halovinyl aldehydes, Vilsmeier-Haack's reaction, DMF/POCl3.