Abstract

PHYTOCHEMICAL PROFILING AND INSILCO DOCKING STUDIES OF WRIGHTIA TINCTORIA AGAINST FOR PSORIASIS

R. Sharmila* and S. Hariprasanth

Abstract

Wrightia tinctoria is a widely used medicinal plant. Phytochemical, antibacterial activities and antipsoriatic activities of bark of W.tinctoria were investigated. The Propanol extracts of W.tinctoria showed the presence of alkaloids, phenolics, saponins, tannins and trepenoids. The antibacterial activities of bark of W. tinctoria tested against Klebsiella pneumonia, Enterobacter sp, Proteus vulgaris, Staphylococcus aureus, E coli, Pseudomonas aeruginosa. However, many species is tested, Enterobacter had a maximum inhibitory effect. Whereas for antipsoriatic activity Insilco studies were performed. Phytocompounds of W.tinctoria has revealed a good result on the inhibition of 1PSR protein. Hence, this study suggested that W.tinctoria has various pharmacological activity such as anti-microbial, anti-psoriatic, antioxidant, etc.

Keywords: Phytochemicals, Wrightia tinctoria, docking studies.