Abstract

EVALUATION OF THE EFFICACY OF JWARAGHNA KASHAYA ON MALARIA

Dr. Wandaka Evalyn G. Lamare* and Dr. B. B. Kadlaskar

Abstract

Aim: To evaluate the efficacy of jwaraghna kashaya Ref: A.H.CH 1/151 (patola, katuka, musta, haritaki & yashtimadhu) on malaria. Objectives:  To observe the antipyretic action of jwaraghna kashaya.  To observe the clinical outcome of jwaraghna kashaya as an adjuvant medicine in malaria. Method: Open Clinical Randomized study conducted on 60 patients, which are divided into two group i,e group A 30 patients and group B 30 patients. Each group received anti- malarial drugs. Additional to this group A also received jwaraghna kashaya. Duration of Treatment: 7 days. This study was carried out at Sahsniang PHC West Jaintia Hills District, Meghalaya in the Year 2015 and 2016. Result: The clinical trial of Jwaraghna kashaya along with antimalarial drugs in group A is observed to be more effective in reducing the clinical symptoms of malaria along with parasite clearance from the blood.  The symptoms of Headache, Nausea/Vomiting, Taste, Myalgia, Giddiness and Fatigue shows highly significant in group A as compared to significant in group B.  The symptoms of intermittent fever, rigor, profuse sweating and cough show equal significant result in both the groups.  The symptom of hepatomegaly and splenomegaly showed no significant results.  In all the symptoms except two, the P-Value is less than 0.05. Therefore; Jwaraghna kashaya is effective in the management of malaria as an adjuvant medicine. Statistical Analysis: The present drug Jwaraghna kashaya along with the statistical analysis and interference shows remarkable improvement in clinical signs and symptoms of Malaria along with parasite clearance in group A as compared to group B. Conclusion: 1) Jwaraghna kashaya is having Jwaraghna (antipyretic), Rakta prasadana (blood purifier), Srotoshodaka (clears the channels), Rasayana (Rejuvenate), Deepan (increases the digestive power), Pachan, Bhedana properties. 2) Jwaraghna kashaya has provided statistically significant results in headache, nausea/vomiting, taste, myalgia, giddiness and fatigue along with parasite clearance. 3) Jwaraghna kashaya has not showed significant result in reducing hepatomegaly and splenomegaly 4) Any side effect has not been observed during and after its clinical trial. 5) In a nutshell, it can be concluded that Jwaraghna Kashaya can be used as an adjuvant medicine on Malaria 6) However this trial was carried out on a very small scale and clinical trials on a large scale are needed which may lead to opening of the new horizon. 7) The clinical study of Jwaraghna Kashaya along with anti-malarial drugs was carried out and it can be concluded that- The evaluation of the Jwaraghna kashaya is effective as an adjuvant medicine in reducing the clinical symptoms of malaria along with reducing and clearing the parasites from the blood. Since Malaria is similar to Vishama jwara which has been studied from different Samhitas and modern books in detail. Likewise detailed study of Jwaraghna kashaya has been carried out.

Keywords: Jwaraghna Kashaya, Malaria, Vishama jwara.