Abstract

PHARMACOGNOSTICAL, PHYSICOCHEMICAL AND HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY EVALUATION OF MASHABALADIKWATHA

Adil Rais*, Divya Zala, Shital Bhagiya, Harisha C. R., V. J. Shukla and Anup B. Thakar

Abstract

Background: Maintaining the quality standard of a polyherbal formulation is a challenging task. Without establishing proper standards for raw materials, it would be very difficult to evolve standards for Ayurvedic drug formulation.In the era of increasing demand for indigenous medicines, maintaining quality standards is the need of the hour. Aim: The present work was carried out to standardize the finished product MashabaladiKwathato confirm its identity, quality and purity.Material and method: Mashabaladikwatha powder was evaluated for their pharmacognostic and pharmaceutical analysis. Results: The presence of Starch grain with hilum of Masha, oil globules of KaunchaBeeja, Cluster crystal of Erandmoola, Spiral vessel of Bala, Lignified border pitted vessel of Erandmoola, Group of starch grains with oil globule of Masha etcwere the characteristic features observed in the microscopy of drug combination. Results found in pharmaceutical parameters of MashabaladiKwatha powder like Loss on drying14.19% w/w, Ash value 9.4% w/w, Water soluble extract 38.7 % w/wetc and specific gravity of Mashabaladi Kwatha was1.016.Authentification of MashabaladiKwathawas cross verified with standard reference API. All the physico-chemical parameters were found to be within the normal reference range.

Keywords: High performance thin layer chromatography, MashabaladiKwatha, Pharmaceutics, Pharmacognosy.