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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

ALOE VERA GEL REVERSES HAEMOSTATIC DERANGEMENT IN RATS FOLLOWING SALT LOADING.

Archibong Nsa Archibong, Clement Oshie Nku, Augustine Lishilinimye Udefa*, Solomon Ayaokpo Leilei

Abstract

This research investigated the effect of Aloe vera (gel) on haemostatic status of high salt loaded rats. Twenty wistar rats (200-250g) were randomly assigned into 4 groups (n=5) thus: control, Aloe (600mg/kg of Aloe vera), Salt-fed [SF] (high salt diet- 8% NaCl in feed and 1% NaCl in H2O) and salt treated [SF+Aloe] (high salt diet+600mg/kg of Aloe vera) groups. All groups took rat feed and water throughout the duration (six weeks) of treatment. Blood samples were collected via cardiac puncture and tail pricking for analysis. Platelet count was significantly decreased in Aloe (p

Keywords: Aloe Vera; Bleeding; Clotting; Salt; Platelet.

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