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Abstract

APHRODISIAC ACTIVITY OF AQUEOUS EXTRACT OF GLYCYRRHIZA GLABRA IN MALE WISTAR RATS

*Sudhir A. Awate1, Rajendra B. Patil1, Prashant D. Ghode1, Ms.Vinita Patole1, Deshbandhu Pachauri1, S.Haja Sherief2

1JSPM’s Rajarshi Shahu College of Pharmacy and Research, Tathawade, Pune -33 (MS)
2Nandha College of Pharmacy and Research Institute, Erode – 638052(Tamilnadu)

Abstract

In the present study, the aphrodisiac activity of aqueous extract of Glycyrrhiza glabra (Leguminocae) roots & rhizomes was investigated. The extract (150mg/kg & 300mg/kg body wt./day) was administered orally by gavage for 28 days. Mount latency (ML), intromission latency (IL), mounting frequency (MF), intromission frequency (IF),weight of animals (gm) were the parameters observed before and during the sexual behavior study at day 0, 7, 10, 14, 21, and 28. The extract reduced significantly ML & IL (p < 0.05). The extract also increased significantly MF & IF (p < 0.05). These effects were observed in sexually active male rats.

Keywords: Glycyrrhiza glabra, Aphrodisiac activity, Male Wistar rats.


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