Abstract

ANTIBACTERIAL ACTIVITY OF SQUID LOLIGO DUVAUCELI AGAINST HUMAN PATHOGENS

Misba M. Shaikh*, Hina Alim, Firdaus Mukhtar Quraishi and B. L. Jadhav

Abstract

The present study was carried out for antibacterial activity of Loligo duvauceli to prevent the emergence proliferation of resistance microbial strain that can make a significant impact in treating microbial infection. The increase in resistance is a global problem, no country is immune to this condition and all major bacterial pathogens have acquired resistance to at least one or more drugs. As resistance is increased, patients are on high risk of severity because of untreated pathogens. Natural bioactive substances have least quantum of side effect than compared to synthetic product. Squid have been known for their bioactive compound like ink and very few studies are done with respect to the bioactivity of their tissue. The present study focus on evaluation of the antibacterial activity of cold methanolic extract and crude ink gland extract from Cephalopod species Loligo duvauceli against four human pathogen Staphylococcus aureus NCIM 5021, Escherichia coli NCIM 2931, Bacillus subtilis CIM 2063, Salmonella typhi NCIM 2501 were used for the activity by agar cup method. The S. aureus strain was found to be more effective than other selected strains. The overall results suggest that the methanolic extract of Loligo duvauceli showed appreciable antibacterial activity against selected human pathogens and it efficacy can be used for pharmaceutical industry.

Keywords: Antibacterial activity, Loligo duvauceli, methanolic extract, inhibition zone.