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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

SYNTHESIZED IRON OXIDE NANO PARTICLES TREATED MCF-7 CELL LINES FROM AQUEOUS LEAVES EXTRACT OF VITEX NEGUNDO

Karnan P.*, Usha R. and Anbarasu A.

Abstract

There are variety of nano particles systems currently being explored for cancer therapeutics, have attracted remarkable in targeted iron oxide nano particles for cancer therapy has increased dramatically in the past 10. However, synthesized iron oxide nano particles treated MCF-7 cell lines were assessed. DAPI staining method, MTT Assay were employed. The result showed that 50% cell viability loss at the dose of in 5.993. The treated cells showed distinct cellular morphological changes indicating unhealthy cells, whereas the control appeared normal in shape. Control cells were irregular confluent aggregates with rounded and polygonal cells.

Keywords: Fe2O3 NPs, Vitex negundo, DAPI, MTT Assay, Control Cells, MCF-7, Cells Lines.

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