Abstract

PRESCRIPTION TRENDS OF GASTRO-PROTECTIVE AGENTS IN TEACHING HOSPITAL

Sai Krishna M.*, Bharathi D. R., Shankar Reddy B. and Vicky Madhav Singh

Abstract

In most of the countries the prevailing disease is gastric related problems for which majority of the population prefer acid suppressant agents. The common indication for which physicians prescribed acid suppressant drugs are GERD followed by peptic ulcer disease followed by with NSAIDs, antibiotics and other drugs to relieve the side effects of drugs. Objectives: To access the pattern to co-prescription of gastro protective agents. Methodology: A Prospective-observational study was carried out for a periods of six months at BMCH& RC Chitradurga, Karnataka. Categorical data were analysed by frequency and percentage calculation method and quantitative data were analysed by means of descriptive statistic measures. Results: Total of 213 subjects proton pump inhibitors are highly prescribed in that pantoprazole 51.7%, drugs which are taken the majority of the prescription were PPI’s 40.37 % and H2 receptor antagonist was 17.37%, Coming to co-prescription of gastro-protective a total of 167 NSAIDs, and 140 antimicrobials in our study. Paracetamol were 50.2%,cephalosporin’s were 45.70%, Dexamethasone, vitamins B complex are highly prescribed. Conclusion: PPIs were mainly prescribed in our study compare to H2 receptor antagonists and other GPS agents. Coprescription with NSAIDs especially paracetamol, antimicrobials especially cephalosporin followed by corticosteroids and some vitamins. Another finding in PPI’s were pantoprazole is highly prescribed. When coming to the prescription of PPI’s the rationality was lacking in the form of un-indicated, incomplete information, frequency etc.

Keywords: PPIs, H2 receptor antagonist, NSAIDs, SPSS, GPS.