Abstract

SYNTHESIS, CHARACTERISATION AND ANTIMICROBIAL STUDIES OF MANGANESE(II), COBALT(II) AND CADMIUM(II) COMPLEXES CONTAINING OXINE AND 2 – PICOLINE

R. Bharathi and Dr. M. Nagarathinam*

Abstract

The complexes of transition metal ions Mn(II), Co(II) and Cd(II) with oxine (8-hydroxy quinoline) and mixed ligand complexes with oxine and 2-picoline have been synthesized. The structural, spectroscopic and thermal properties have been studied on the basis of Infrared spectra, TGA-DTA analysis, X-ray diffraction analysis and Molar conductivity measurements. From the results obtained the following general formula has been given for the complexes [M(oxine)2] and [M(oxine)2(2-pic)2]. The oxine complexes exhibit antiseptic, disinfectant and pesticide properties. So the metal complexes have been tested against microorganisms using Agar well diffusion method in order to assess their antimicrobial properties. The metal complexes were screened for antibacterial activity against gram negative (Escherichia coli) and gram positive bacteria (Bacillus subtilis) and the fungal activity against Aspergillus niger and Penicillium chrysogenum.

Keywords: Transition metal complexes, oxine, 2-picoline, Thermal Analysis, Antimicrobial studies.