Abstract

ANTIBACTERIAL ACTIVITY OF ECO FRIENDLY SYNTHESISED ZERO VALENT IRON OXIDE NANOPARTICLES

A. Dinesh Karthik*, D. Shakila, K. Geetha and P. Bhavani

Abstract

The emergence of nanoscience and nanotechnology in the last decade presents opportunities for exploring the bactericidal effect of metal nanoparticles. The bactericidal effect of metal nanoparticles has been attributed to their small size and high surface to volume ratio, which allows them to interact closely with microbial membranes and is not merely due to the release of metal ions in solution. In contrast, gram negative bacteria have a relatively thin cell wall consisting of a few layers of peptidoglycan. Surfaces of iron nanoparticles affect or interact directly with the bacterial outer membrane, causing the membrane to rupture and killing bacteria. Antibacterial activity of Zero valent iron oxide nanoparticles (ZVIO) synthesized by Eco friendly synthesis was evaluated by using standard Zone of Inhibition (ZOI) microbiology assay. Zero valent iron oxide nanoparticles (ZVIO) were synthesized using Iron (II) Precursor by Eco friendly method. Zero valent iron oxide nanoparticles (ZVIO) so obtained were characterized by UV- Visible spectroscopy, Fourier Transform Infrared Spectroscopy, and X-Ray diffraction analysis. X-Ray diffraction analysis proved the formation of Zero valent iron oxide nanoparticles (ZVIO) Zero valent iron oxide nanoparticles (ZVIO). SEM analyses showed the presence of nanocrystals. The Zero valent iron oxide nanoparticles (ZVIO) thus formed was subjected to Anti Microbial activity.

Keywords: Fe (II) p-aminobenzoate, UV –Visible, XRD, FTIR, SEM and Antimicrobial activity.