Abstract

THERMAL STABILITY OF SOME BIOLOGICALLY ACTIVE FUNCTIONALLY MODIFIED POLY (VINYL ALCOHOL)

P. Narendiran and S. Guhanathan*

Abstract

Polymers form a very important class of materials without which the life seems very difficult. It has been believed that the antimicrobial activity of the compound mainly due to the presence of heteroatoms like nitrogen and phosphorous as similar to the naturally occurring polymers viz., DNA, proteins etc., incorporation of heterocyclic functionality to the synthetic polymers found to exhibit the biological activity to the existing polymers than their unmodified polymers. Based on the literature, the present work have been designed to have benzodiazepine functionalized vinyl polymers like Poly (vinylalcohol). Functionally modified PVA have been characterized by spectral (FTIR, 1H-NMR and 13C-NMR), thermal (TGA) analysis. Functionally modified PVA have also been subjected into antimicrobial studies. Results of the investigation reveals that the functionally modified PVA exhibited good thermal stability and moderate antimicrobial action against unmodified PVA.

Keywords: Chalcones; benzodiazepines; functional modification; thermal stability; antimicrobial activity.