Abstract

SYNTHESIS, CHARACTERISATION AND ANTI MICROBIAL ACTIVITY OF A NOVEL POLYMERIC COPPER (II) COMPLEX

M. A. Rajalakshmi, A. Dinesh Karthik and Kannappan Geetha*

Abstract

A novel polymeric Copper (II) complex containing [{Cu2L (O2CCH2NH2)}]X pentadentate Schiff base ligand has been prepared from the precursor complex pentadentate Schiff base ligand. The precursor complex was prepared from 1:2:2 molar ratios of Copper sulphate, glycine and sodium hydroxide. The synthesized polymeric Copper (II) complex was characterised by using UV-Visible spectra and FT-IR spectra. The synthesized Copper (II) complex and the precursor and the Schiff base ligand were screened for their antibacterial activity against Staphylococcus aureus, Klebsiella pneumonial, E-Coli, Pseudomonas aeurginosa and antifungal activity against Aspergillus niger, Penicillium spp. Candida tropicalis and Candida albicans. The complex was found to be inhibitory to all the selected micro organisms except Aspergillus niger and Penicillium spp. Both Schiff base ligand and precursor didn‟t show any inhibition to all the selected micro organisms.

Keywords: Copper (II) complex, E-Coli, Pseudomonas aeurginosa and Candida albicans.